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How tramadol causes respiratory depression
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Author:  Buytramadolusa [ August 26th, 2024, 2:22 am ]
Post subject:  How tramadol causes respiratory depression

In clinical practice, respiratory depression has been documented with tramadol treatment for cancer pain in individuals with renal impairment. This is due to the accumulation of the active metabolite (M1), which has a longer elimination half-life than the parent medicine and binds to μ opioid receptors.
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